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Polyphenols, widely consumed plant-derived compounds, have demonstrated protective effects on the cardiovascular and cerebrovascular systems, with emerging evidence from preclinical stroke models highlighting their neuroprotective potential, even when administered post-stroke (Parrella et al., 2020)

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To date, clinical trials have not shown a significantly higher risk profile for retatrutide compared to tirzepatide, provided that titration protocols are strictly followed in the research design

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