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In the Xu 2024 heart-failure study the compound improved cardiac function rather than worsening it

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In addition, ginsenoside Rbl can improve cardiac function and remodeling in patients with heart failure, and the mechanism may be that ginsenoside can not only reduce -myosin heavy chain (MHC), angiotensin I converting enzyme (ACE), angiotensin II (AngII) and atrial natriuretic factor (ANF), but also regulate mitochondrial membrane potential (Zheng et al., 2017b)

[DOI] [PMC free article] [PubMed] [Google Scholar] 255.Thakkar A., Sutaria D., Grandhi B