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[91] Since only bacteria and some archea possess the genes and enzymes necessary to synthesize vitamin B 12 , plant and algae sources all obtain the vitamin secondarily from symbiosis with various species of bacteria, [5] or in the case of fermented plant foods, from bacterial fermentation

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Researchers at Eli Lilly engineered it with strategic amino acid substitutions that allow it to activate both the GIP receptor and the GLP-1 receptor simultaneously