Upon activation, free radicals such as nitric oxide (NO) and superoxide are released, which elevates oxidative stress contributing to pathogen elimination and local tissue damage ( Migraine Pathogenesis: Role of Oxidative Stress, Neuroinflammation, and Mitochondrial Dysfunction Migraine is defined as a neurovascular disorder involving cortical spreading depression (CSD), neurogenic inflammation, and dysfunction in cranial vascular contractility ( Oxidative Stress Oxidative stress role in migraine pathogenesis is emphasized by multiple studies
It may actually accelerate it
It provides a controlled tool for studying fat metabolism, energy balance, and adipocyte function without systemic growth hormone effects
Li Q, Yin X, Wang W, Zhan M, Zhao B, Hou Z, et al