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In human observational studies, both the AEDG peptide and its parent extract epithalamin were associated with significant telomere length increases in blood cells of subjects aged 6080, with a separate study documenting an 1119% increase in telomere length in subjects aged 6080 receiving the pineal peptide bioregulator (5)

Typical protocols run 6 to 12 weeks

Once the protocol is active, follow-ups are scheduled at 4 and 8 weeks for adjustment

Although not well explored in tendon formation, knockdown of LOXL2 in chondrogenic cell lines blocks further chondrogenesis through increases in SNAIL, a transcriptional repressor of cadherins, and decreases in SOX9, a transcription factor and key regulator of chondrogenesis (Iftikhar et al ., 2011)