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Nine rats were randomly chosen from each group for gingival tissue vascular permeability measurements, whereas the remaining animals were used for soft tissue histology

Evidence remains largely preclinical, highlighting the experimental nature of BPC-157 for digestive health

Long-term considerations Most safety data on AOD 9604 comes from studies lasting 12 weeks or less

doi: 10.3389/fncel.2025.1588645 Received 06 March 2025 Accepted 14 April 2025 Published 20 May 2025 Volume 19 - 2025 Edited by Neville Ng, University of Wollongong, Australia Reviewed by Mingzi Zhang, University of Southern California, United States Slawomir Jakiela, Warsaw University of Life Sciences, Poland Vasileios Balis, Aegean College, Greece Updates Copyright 2025 Liu, Sun, Guo, Yuan, Zhu, Lu, Chen, Qu, Feng and Yang