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doi: 10.1016/j.microc.2023.109231 91 SabirAMMoloyMBhasinPS

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Among the multiple biological activities of astaxanthin, its antioxidant, anti-obesity, and muscle-related effects were selected as the main focus of this review because these domains are mechanistically interconnected through oxidative stress regulation, mitochondrial bioenergetics, and energy homeostasis, and are the most consistently supported by preclinical and clinical evidence

Mitochondrial abnormalities have also been associated with point mutations in Hsp70 chaperone that makes it aggregation prone, thereby, increasing iron and free-radical load 15,16,17