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Plausible degradation pathways include: Serum aminopeptidases (cleaving from the N-terminus) Endopeptidases (internal bond cleavage) Hepatic uptake and degradation Renal clearance (though direct renal excretion of intact peptide of this size is typically limited) Whether BPC-157 generates active metabolites i.e., smaller peptide fragments that retain biological activity is not established in the public literature

Preclinical studies suggests BPC 157 has the following effects: Reduced inflammation of the gut and enhanced repair of the intestinal lining

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Extracellular vesicles from nanomedicine-trained intestinal microbiota substitute for fecal microbiota transplant in treating ulcerative colitis