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No difference in serum levels of glutamate has been reported between children with autistic disorder and controls [69, 70], however, it was significantly higher in adults with autistic disorder [75], the level being positively correlated with social functioning as measured by the autism diagnostic interview (ADI-R) [103] which is commonly used to evaluate the core symptoms of autism which may shed light on the significantly higher level detected in mixed samples of children with autism spectrum disorders [86, 87]

Adusumilli VS, Walker TL, Overall RW, Klatt GM, Zeidan SA, Zocher S, et al

Auto-fluorescence was reduced by incubating the tissue sections in Image-iT FX Signal Enhancer (Thermo Fisher) for 30 min at room temperature

Aif3 splicing variant elicits mitochondrial malfunction via the concurrent dysregulation of electron transport chain and glutathione-redox homeostasis