what is a melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Oral pathology: Noting a pigmented

PMID: 29 GhasemiFShafieeMBanikazemiZPourhanifehMHKhanbabaeiHShamshirianAet al

In murine bleomycin models, 20 additional ferroptosislinked genes (e.g., ALOX15, CDO1, JUN, SLC2A1, GPX2) were differentially expressed in fibrotic versus normal lung ( Taken together, these biomarkers capture complementary facets of ferroptosisupstream iron dysregulation, core lipid peroxidation events, failed antioxidant defenses, and downstream gene expression changes

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