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Isopsoralen alleviated joint bone erosion and inhibited RANKL-induced osteoclast formation by blocking the NF-B signaling pathway ( Artemisia dracunculus significantly increased osteogenic gene expression and increased mineralization ( In general, bioactive components of TCM can inhibit the proliferation and migration of fibroblast synovial cells, reduce osteoclast differentiation, bone resorption and cartilage degradation, and resolve the inflammation of RA

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Evidence suggests mixed outcomes depending on treatment duration and individual skin factors

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