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SAM is additionally required for phosphatidylcholine synthesis, which is abundant in neuronal membranes and is crucial for synaptogenesis and neurite outgrowth ( Vitamin B12 is a cofactor for the enzyme methylmalonyl-CoA mutase, which converts methylmalonyl-CoA to succinyl-CoA, a crucial step in fatty acid metabolism (73)

no aspiration) Subcutaneous Drug Injection Review (PMC) Pharmacologic considerations of the subcutaneous route Additional Research and Background These sources provide related context and are not presented as support for a specific statement above

When Injections Are Medically Indicated People with certain issues might need B12 injections

However, B12 shots provide a more immediate effect because they deliver the vitamin directly into your bloodstream, bypassing the digestive system