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The choice between subcutaneous and intramuscular administration may depend on the formulation, the patients body composition, and the clinics experience

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The injection requirement for most peptide drugs may limit their use in certain patient populations, such as those with needle phobias or limited ability to self-administer injections

(2006) tested topical copper tripeptide complex on skin healing after CO2 laser resurfacing in a controlled study comparing three treatment groups: copper peptide cream, tretinoin (retinoic acid) cream, and vitamin C cream