Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance
Adv Funct Mater2020, 2004272
As put by the authors of a 2019 review on drug-phospholipid complexes, the combined affinity for fats and water means that phospholipids function as emulsifiers that enhance absorption and, therefore, bioavailability.4 Indeed, a 1990 human study found that a silymarin-phospholipid complex resulted in plasma levels of silybin (silymarin's main active component) that were more than double the amount provided by an equal quantity of pure silymarin 298ng/mL versus 102ng/mL per 120mg of silybin.34 Given the science behind phospholipid-based drug delivery, we can conclude that Life Extension is likely capable of delivering more per-dose silymarin, as well as isolated silybin, than either NOW or HUM (neither of which uses phospholipids)
This being said, it would be great to see full data, hopefully including changes in body composition and physical fitness - if not here, then perhaps in some later trials Looking forward to full data presentation and also to further trials looking into possible cardioprotective and nephroprotective effects and influence on other complications of obesity #cagrisema #tirzepatide #cagrilintide #semaglutide #obesity #weightloss #REDEFINE4 To view or add a comment, sign in More Relevant Posts As a next-generation combination, CagriSema was widely expected to at least match tirzepatides efficacy in REDEFINE-4
