As long as it works, who cares?" We've seen this line of thinking before, and honestly, it can lead to compromised data and frustrating inconsistencies
Thorakkattu P, Khanashyam AC, Shah K, Babu KS, Mundanat AS, Deliephan A, Deokar GS, Santivarangkna C, Nirmal NP (2022) Postbiotics: current trends in food and pharmaceutical industry
However, the ability of colistin to penetrate the lungs is limited
The elevation in cAMP also stimulates protein kinase A which phosphorylates and activates the transcription factor CREB (cAMP response element binding protein), which then stimulates de novo GH production via transcription of the GH1 gene as well as increasing transcription of the GHRH receptor gene as part of a short positive feedback loop To summarize all of this in one sentence GHRH is responsible for both the production and secretion of growth hormone