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Nierenberg AA, Ostacher MJ, Calabrese JR, Ketter TA, Marangell LB, Miklowitz DJ, et al

Specific peptides inhibiting NLRP3 inflammasome showing promise in preclinical research

J Biol Chem 281(40):2956829574

found that HIF-1 was positive in muscle biopsy samples of juvenile DM (jDM, DM patients under 16 years old), accompanied by significantly elevated HIF-1 expression levels as indicated by mRNA data