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Besides cancer heterogenicity and specificity, some other issues still exist in cancer treatment by ACPs

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When injected into a monkey model of endometriosis with its long-acting recovery antibody (AMY109), IL-8, a potent chemoattractant for angiogenic factors and immune cells, can inhibit neutrophil recruitment to endometrial lesions and suppress their production of monocyte chemotactic protein-1, thereby ameliorating endometriosis inflammation and fibrosis (59)