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Antunes dos Santos A, Ferrer B, Marques Gonalves F, Tsatsakis A, Renieri E, Skalny A, Farina M, Rocha J et al (2018) Oxidative stress in methylmercury-induced cell toxicity

However, many of these approaches have limitations, such as environmental concerns associated with the use of parasiticides, acaricides, and insecticides

Additionally, if they compete with other P-gp substrates, they may impact the pharmacokinetics of co-administered drugs, potentially altering their therapeutic effects

Western blot analysis further showed that cartilage generated from FOXO4-DRI pre-treated chondrocytes displayed higher protein levels of p16, p21, and p53 (Figure 3B)