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Science 333:14561458 Chew LJ, Takanohashi A, Bell M (2006) Microglia and inflammation: impact on developmental brain injuries

3.2.1 Steroidogenic enzyme inhibition 3.2.1.1 17-hydroxysteroid dehydrogenase (HSD17B) suppression Cadmium exposure directly inhibits HSD17B enzymatic activity with an IC50 of 2.2 M, resulting in an 85% reduction in testosterone synthesis capacity

Patients report a distinctly higher level of physical performance, faster recovery, better body composition, and improved overall quality of life compared to TRT alone

This means looking at your hydration, your stress management, and your diet alongside your supplement routine