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To understand why this happens, we have to go to the synaptic cleft, or the connection between neurons

Sources Vitamin B12 - Consumer | National Institutes of Health VITAMIN B12: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews | WebMD Article Vitamin B12 Deficiency: Causes, Symptoms, and Treatment | WebMD Living longer isnt enough if you dont feel your best

The downstream effects most consistently described in the literature: induction of collagen I and III, elastin, and decorin synthesis (Maquart et al., FEBS Letters , 1988), upregulation of VEGF and basic FGF transcripts, induction of antioxidant defense genes including SOD2 and metallothionein isoforms, and modulation of the MMP-2 and TIMP-1/2 balance toward non-fibrotic remodeling

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