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Collectively, these processes lead to the perpetuation and maintenance of a pro-inflammatory environment within the islet, ultimately culminating in -cell dysfunction, death and T2D (2) ( Figure 1 )

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Exhaustive multi-parametric assessment of the behavioral array of daily activities of mice using cluster and factor analysis

Nonetheless, the oral administration of HSP (~ 20%) is constrained by its low aqueous solubility 5 , insufficient intestinal absorption, metabolism by phase II enzymes, and efflux by enterocytes