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Combination Therapy with Levothyroxine and Liothyronine If traditional LT4 monotherapy results in a relatively lower serum T3 concentration accompanied by some patient dissatisfaction with this therapy, this might prompt consideration of combination therapy with both LT4 and LT3 (1, 157, 167)
Gut dysbiosis and disrupted intestinal barrier function could worsen pulmonary symptoms, augment neurological or hepatic inflammation through translocation of endotoxins and bacteria via portal veins 239,240,241
