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Oxidative stress is caused by an imbalance in the rate of free radical formation and detoxification, which ultimately triggers ferroptosis via lipid peroxidation[20]

Milella M, Kornblau SM, Estrov Z, Carter BZ, Lapillonne H, Harris D, Konopleva M, Zhao S, Estey E, Andreeff M

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However, OS can also directly be involved in the pathogenesis of urinary symptoms: there is, indeed, evidence that OS can promote bladder dysfunction, impair detrusor contraction, and result in bladder hyperactivity [169]