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Description

Briefly, DiffVar builds on Levenes test for equality of variances and employs an empirical Bayes modeling framework to stabilize the test statistics

doi: 10.1093/toxsci/51.2.161

The compound functions as a synthetic D-retro-inverso peptide carrying a shortened version of the FOXO4 segment that binds to p53, acting as a competitive inhibitor of this critical protein-protein interaction

For all datasets, a representative class from the end of 3D classification was low-pass filtered to 40 to avoid bias and used as a reference during refinement