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Zinc dysregulation within the endolysosomal system also intersects with cancer biology: the alcohol-deterrent and emerging anticancer agent disulfiram disrupts endolysosomal structure and raises intraluminal zinc in breast cancer cells, implicating zinc dysregulation in its cytotoxicity and suggesting that extracellular zinc availability modulates its efficacy 169

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Don't let their size fool you, these 7 small dogs have larger-than-life personalities Small in size but overflowing with personality, these energetic dogs know exactly how to make every day more exciting