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SLC22A12 gene encoding for the urate transporter hURAT1 defects leads to primary renal hypouricemia characterized by increased UA excretion from a reduced reabsorption ( SLC2A9 gene, encoding the urate transporter GLUT9, are closely related to human cognition and neurodegenerative diseases ( Urate Transporters and Genetics of Urate Transporter Pathologies A series of urate transporters including SLC and ABC transporters as well as several multispecific drug transporters (e.g., OAT1, OAT2, and ABCG2) maintain UA homeostasis (Figure 2) (Table 1)

[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Gojkovic S., Krezic I., Vranes H., Zizek H., Drmic D., Batelja Vuletic L., Milavic M., Sikiric S., Stilinovic I., Simeon P., et al

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