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Brain endothelial tight junction proteins include occludin, claudins (claudin-1, 3, 5, 12), and the membrane-associated guanylate kinase (MAGUK) protein family of zonula occludens (ZO1, ZO2, and ZO3) (Fig

Current Pharmaceutical Design , 2020 In various studies, BPC-157 was observed to: Accelerate healing of muscle, tendon, ligament, nerve, and gut tissue Reduce inflammation, fibrosis, and oxidative stress Protect organ systems (gut, liver, brain) under chemical or surgical stress Stabilize blood vessels and prevent internal bleeding in injury models Importantly, these effects occurred without toxicity , even when administered in high or repeated doses