The mode of action and use of chlorothiazide and related compounds
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Hu et al., 2017), Rett syndrome and MECP2 mutations with the resulted repetitive and stereotypic/restricted behaviors, abnormal gait and reduced anxiety, decreased pain and normal olfactory discrimination (Chao et al., 2013), tuberous sclerosis TSC1 or TSC2 with social interactions deficits and repetitive/restricted behavior or interest (Chao et al., 2011), Timothy syndrome (TS) CACNA1C with impairments in social interactions, repetitive/stereotypic behaviors, and increased fear conditioning (Ergaz et al., 2016), Phelan-McDermid syndrome with restricted interest as well as cognitive and motor deficits (Giza et al., 2010
After isolation of the target DNAprotein complexes, Proteinase K was added to degrade the protein components within the complexes, and the purified DNA products were recovered