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Moreover, we validated the relationship between GSH-regulated replication stress and JMF4073 sensitivity in a number of TKI-insensitive human CML blast-crisis cells, and present the evidence of the synthetic lethality by targeting glutathione biosynthesis with JMF4073 in these cells
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Therefore, only the backbone is modelled in the final pdb file
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
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