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Asian Pac J Cancer Prev 16(6):21292144

4.1.7 Fbxl4 Fbxl4 is a Clock-regulated E3 ubiquitin ligase that links molecular circadian oscillators to neuronal excitability and sleep timing in Drosophila ( Fbxl4 transcript levels cycle rhythmically in the large ventral lateral neurons (lLNvs) and are driven directly by Clock-cycle binding to E-box elements within the fbxl4 promoter ( A receptors in lLNvs, thereby reducing GABA sensitivity and enhancing neuronal excitability during the wake phase (Parisky et al., 2008

Addition of DNase I and reduced glutathione (GSH) significantly reduced biofilm biomass of pyocyanin-producing strains ( P 150 M)