Weekly behavioral support and assessments (weeks 113) Participants in all groups will receive brief behavioral support weekly and be asked about their smoking status, adverse events, and concomitant medication
The effects of nicotine on the central nervous system (CNS) and its peripheral stimulating effects are mediated through the release of several neurotransmitters, including acetylcholine, beta-endorphin, dopamine, norepinephrine, serotonin, and adrenocorticotropic hormone (ACTH) [18]
This occurs because mood regulation, memory, willpower, and decision-making processes are all significantly impacted by the use of substances
Social influence-based interventions like ASSIST may be particularly beneficial in more deprived areas or in LMICs lacking strong tobacco control legislation, where smoking remains largely normalized (Littlecott et al., 2023