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In line with the principles of 21 st century toxicology, PMI is also developing novel in vitro methods for toxicity testing using human cells

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Dosimetry, a major issue Different ways to express doses and different dose ranges used When considering the studies dealing with the toxicity of e-cigarettes assessment, in addition to the heterogeneity of e-cigarette products, biological models, or exposure conditions observed, there is also a huge disparity in the doses used as well as in the way they are expressed as shown in Table 2

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