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Antithyroid medications are not recommended because the mechanism associated the secretion of preformed hormones from the thyroid follicles as a result of deleterious inflammatory response

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Therefore, the use of nano-DDS to exogenously supplement cancer cells with extra polyunsaturated fatty acids to exogenously regulate lipid peroxidation is also an effective strategy to improve the therapeutic effect of ferroptosis-driven cancer treatment [209,210,211]