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Case series, such as that described by Lotz-Havla et al

Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease

Using one needle for both caused itch problem

If you are comparing the two for your protocol, the side effect profiles and dosage equivalencies are covered in separate guides