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www.ajpbp.com

doi: 10.1080/19490976.2023.2281360, 16 CaiT.ZhengS

No phase 2 or 3 human trial has established an optimal oral dose

Specifically, circulating ALCAR was found to be reduced in patients with severe osteoarthritis pain that did not improve after a total joint replacement (Costello et al., 2020)