They are used to correct imbalances in the MGBA and may help slow disease progression (Kesika et al., 2021)
Clinically, liver injury manifests as a sharp rise in transaminases, abnormal bilirubin metabolism, and coagulation dysfunction, often combined with damage to the heart, brain, kidneys, and other organs, constituting MODS
As discussed in gut health research more broadly, microbiome disruption drives: Intestinal permeability Systemic inflammation Impaired neurotransmitter production Immune dysregulation In the context of long COVID, gut dysfunction may represent both a consequence of the initial infection and an ongoing driver of systemic inflammatory and neurological symptoms
Figure 6.7 Operating Leverage Example One way to observe the importance of operating leverage is to compare the break-even point in sales dollars for each company