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Low GSH has been linked to abnormalities in the lung surfactant system and the interaction between GSH and antiproteases in the epithelial lining fluid of patients

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Pro-inflammatory cytokines like IL-1 and TNF- have been labeled as the major destructive compounds contributing to cartilage loss in the ECM, but MSM could exhibit protected effects on cartilage by suppressing the effects of IL-1 and TNF- 5, thereby preventing degradation

[DOI] [PubMed] [Google Scholar] 60.Brown K.E., Meleah Mathahs M., Broadhurst K.A., Coleman M.C., Ridnour L.A., Schmidt W.N., Spitz D.R