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Health Canada said it is adopting "the most comprehensive measures" on plain packaging

In short, yes smoking can seriously affect your immune system [2]

[DOI] [PubMed] [Google Scholar] 95.Soler P, Moreau A, Basset F, Hance AJ

The following factors were included as covariates for potential confounders or risk factors: sex (male or female), grade (7th, 8th, 9th, 10th, 11th, or 12th), academic performance (high, middle, or low), area of residence (metropolitan, urban, or rural), residence type (living with or without family), economic status (high, middle, or low), subjective health condition (healthy, normal, or unhealthy), physical activity over 1 h and five times per week (yes or no), drinking experience (yes or no), smoking status (never, ex-smoker, or current smoker), sleep satisfaction (satisfied, regular, or unsatisfied), stress perception (high, middle, or low), depressive symptoms in the past 12 months (yes or no), and year (2020, 2021, 2022, or 2023)