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2024 Dec 31:111368

-3 PUFAs alleviate high-fat diet-induced circadian intestinal microbes dysbiosis (in Eng)

Not wrinkled exactly, but almost like when someone has very sun-damaged skin or overly smooth Botox skin that doesnt look natural. Whether copper uglies is a real phenomenon or merely an Internet myth is unclear

Taken together, these observations support a model in which BL mitigates PD-associated neurodegeneration through multimodal anti-inflammatory mechanisms, including inhibition of NF-B nuclear translocation, downregulation of p65 signaling, suppression of NLRP3 inflammasome assembly, and reduction of pro-inflammatory cytokine production