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Proc Natl Acad Sci U S A 95(11):64696473 Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ (2010) CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

Fumarylacetoacetate is hydrolyzed to fumarate and acetoacetate by the enzyme fumarylacetoacetate hydrolase which is encoded by the FAH gene

During the process of phospholipid hydroperoxide being reduced to the corresponding phospholipid alcohols, GSH acts as an electron donor, while glutathione disulfide (GSSG) is produced simultaneously (51)