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It is generally thought that biotin is transported along with pantothenic and lipoic acids by the sodium-dependent multivitamin transporter (SMVT)

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Based on the pharmacokinetics of Lcarnitine, we advocate the administration of Lcarnitine for valproicacid induced hyperammonaemia or hepatotoxicity as an intravenous loading dose of 5 mg/kg followed by a continuous intravenous infusion instead of the oral or intravenous boluses that are currently advocated

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