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These groups can be divided into 4 major parts (Figure 6): 1-Core Ring which contains side chains 2-Beta legend, Adenosine and methyl cobalamine functional groups 3- Nucleotide moiety which is a Benzimidazole moiety that is an alpha glycosidic bonded benzimidazole and bonds coordinately to cobalt atom in the core ring and is essential for biological activity 4- Aminopropanol residue that links between the side chain of the core ring and the Nucleotide moiety