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Emergency department utilization is particularly elevated, with 67% of women visiting emergency departments for pain-related complaints before receiving their diagnosis (Fuldeore & Soliman, 2017)

Reactive oxygen species (ROS), together with reactive nitrogen species (RNS), represent the most important prooxidants whose excessive accumulation leads to oxidative stress (OxS) and molecular damage ( ROS are crucial in thyroid function because they are essential in the initial stages of thyroid hormone synthesis during iodide oxidation ( Aerobic organisms have evolved multiple antioxidant and repair systems for protection against OxS

Kurian et al., 2016