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Activation of the p62-Keapl-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

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however, lack of interactions from the catechol group, as observed in docked poses and MD analysis, predicted to cause weak or no mh-Tyr inhibition by comparison to other selected flavonoids (EC and CH) due to rapid oxidation in the catalytic pocket of the mh-Tyr protein