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Stem Cell Res Ther 16(1):364 Xiu Z, Tang S, Kong P, Yan M, Tong X, Liu X, Liang X, Li R, Duan Y (2023) Zigui-Yichong-Fang protects against cyclophosphamide-induced premature ovarian insufficiency via the SIRT1/Foxo3a pathway

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Adding GHK-Cu during the remodeling phase is optional and more relevant for chronic conditions where tissue quality has deteriorated

Active or history of certain cancers: Due to GHK-Cu's growth factor-like effects and angiogenesis promotion, it should be avoided by individuals with active cancer or a history of certain cancers