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In a pilot study during 1 month of four patients with Crohns disease the mean serum cobalamin concentration increased significantly after weekly administration of 1500 g of the same formulation

Given these potential mechanisms, this study was designed to test the hypothesis that DIO mice restored to the weight and adiposity of LD controls through NNMTi treatment and LD switch 13 have a similar microbiome profile to mice continuously maintained on LD