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Description

Complementary, this finding was confirmed by flow cytometry (flow cytometry plots: Fig

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2j,k and Extended Data Fig

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The peptide upregulates MMP-2 expression in dermal fibroblasts by 85%, facilitating breakdown of damaged collagen and enabling cellular migration through dense matrix environments, while simultaneously enhancing production of tissue inhibitors of metalloproteinases (TIMPs) to prevent excessive degradation

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Heffernan, M., Summers, R

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