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Wound Closure In animal models, the healing data is consistent across multiple setups: Ischemic wounds (rats): GHK-Cu treated wounds healed faster, with decreased MMP-2, MMP-9, and TNF- levels vs

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These pharmacokinetic challenges undermine its sustained efficacy, and the need for frequent dosing may elevate the risk of adverse effects, further limiting its clinical utility

The measured activities were compared with formerly determined specific activity values 19 in order to assess the concentration of active enzyme in cases of divergence between the values