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The model was defined by two differential equations: A and C are the amounts of drug in the depot and central compartments, k a and k el are the first-order absorption and elimination rate constants, V/F is the volume of distribution, F is the bioavailability (assumed equal to one), and Cp is the drug concentration in the central compartment

PRP has been shown to stimulate collagen production and reduce degenerative changes at the cellular level, directly addressing the underlying pathology of chronic tendinopathy (PMID: 29524997)