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We summarize the physiological roles of lactate in neuronalglial metabolic coupling and highlight cell-type-specific functions of the lactatelactylation axis under both normal and pathological conditions

There was a positive trend in the Composite SLE Responder Index in the Intention-to-treat (ITT) cohort, and post-hoc analysis showed that the BILAG secondary endpoint was met for a number of subgroups dosing levels, including low or no steroids, seropositivity, and patients with 2 grade BILAG improvement

This timing allows the injection site to settle while maximizing synergy between systemic and topical delivery

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